彻底

He is mad, stark mad.

encounter/receive/suffer a thorough defeat

gain/achieve a complete victory; secure a sweeping victory

effect a permanent cure

utterly/completely destroy/eliminate; totally wipe out; totally eradicate

uproot poverty

be finished for good

make a total confession (of)

search exhaustively/thoroughly (for sb/sth); ransack (sth for sth else)

go into complete bankruptcy

make a complete/clean break (with sb/sth); break completely (with sb/sth)

settle sth once and for all; find a radical solution

expose completely/thoroughly

do a complete/thorough overhaul (of sth)

carry out a thorough inspection (of sth); give sth a thorough inspection; examine thoroughly

make/effect/conduct a thoroughgoing reform; carry out a sweeping/radical reform

make a thorough/an exhaustive/a sound investigation (into/of sth); investigate thoroughly

give sth a thorough/clean sweep; clean thoroughly

destroy sth root and branch; strike at the root(s) completely; uproot; eradicate thoroughly